Eastern Region KCSE 2022/2023 Best 100 Girls’ Secondary Schools in Kenya
| Position Nationally | Name of School | Region | County | Mean Score | Mean Grade | Type | Knec Code |
| 24 | KAAGA GIRLS | Eastern | meru | 9.96 | B+{plus} | Girls | |
| 59 | Mt Carmel girls | Eastern | Makueni | 9.2353 | B{plain} | Girls | |
| 69 | KATHIANI GIRLS HIGH | Eastern | Machakos | 9.1235 | B{plain} | Girls | |
| 86 | Mbooni Girls | Eastern | Makueni | 8.911 | B{plain} | Girls | |
| 119 | AIC Sombe Girls | Eastern | Kitui | 8.545 | B{plain} | Girls | |
| 169 | MUTHALE GIRLS HIGH | Eastern | kitui | 8.11 | B-{minus) | Girls | |
| 192 | Precious Blood Kilungu | Eastern | Makueni | 7.92 | B-{minus) | Girls | |
| 217 | CARING HEARTS HIGH SCHOOL | Eastern | Machakos | 7.76 | B-{minus) | Girls | |
| 243 | St. Josephs Kibwezi | Eastern | Makueni | 7.488 | C+{plus} | Girls | |
| 244 | ST JOSEPHS KIBWEZI | Eastern | Makueni | 7.488 | C+{plus} | Girls | |
| 247 | MISYANI GIRLS HIGH | Eastern | Machakos | 7.4823 | C+{plus} | Girls | |
| 279 | Mwaani Girls | Eastern | Makueni | 7.209 | C+{plus} | Girls | |
| 292 | Kisau Girls | Eastern | Makueni | 7.165 | C+{plus} | Girls | |
| 295 | Machakos Girls | Eastern | Machakos | 7.1406 | C+{plus} | Girls | |
| 301 | Makueni Girls | Eastern | Makueni | 7.102 | C+{plus} | Girls | |
| 320 | OUR Lady of Assumption tawa | Eastern | Makueni | 7.02 | C+{plus} | Girls | |
| 330 | Maua Girls High | Eastern | Meru | 6.96 | C+{plus} | Girls | |
| 332 | ST ANGELAS GIRLS SECONDARY | Eastern | Kitui | 6.935 | C+{plus} | Girls | |
| 462 | St. Catherine | Eastern | Machakos | 5.613 | C (plain) | Girls | |
| 464 | Mulala Girls | Eastern | Makueni | 5.6 | C (plain) | Girls |
