Orero High School emerged the best school in the KCSE 2021/2022 exams in County with a mean score of 9.4083 which is a B (plain).
2021/2022 BEST, TOP PERFORMING SCHOOLS IN HOMA BAY COUNTY
| Pos Nationally | School Name | Mean Score | County | |
| 14 | Orero High School | 9.4083 | B | Homa Bay |
| 17 | Gendia High School | 9.3121 | B | Homa Bay |
| 23 | Mbita High School | 9.1595 | B | Homa Bay |
| 31 | Moi Girls High Sindo | 9 | B | Homa Bay |
| 42 | Asumbi Girls High School | 8.812 | B | Homa Bay |
| 43 | Ober Boys Secondary | 8.8 | B | Homa Bay |
| 57 | Agoro Sare High School | 8.5 | B | Homa Bay |
| 74 | Nyalenda Mixed Secondary | 8.2264 | B- | Homa Bay |
| 78 | Bishop Linus Okok Girls | 8.2 | B- | Homa Bay |
| 87 | Saye Mixed Secondary | 8.049 | B- | Homa Bay |
| 95 | Tonga Boys | 8 | B- | Homa Bay |
| 124 | Homa Bay High School | 7.306 | C+ | Homa Bay |